Datura fastuosa L., Datura alba Nees.
Family: Solanaceae

Bengali/vernacular name: Dhutra, Dhutura.
Tribal name: Dhutura (Tanchangya).
English name: Datura, Thorn-apple.

Description of the plant:
A coarse, shrubby annual, 0.9-1.2 m high. Leaves 15-20 cm long, ovate, acute, entire or with few large teeth or lobes. Flowers solitary, calyx 7.5 cm long, tubular, corolla about twice as long as the calyx, tubular, widend at the mouth, purple or white, often double. Capsules subglobose, nodding, covered all over with numerous, straight, sharp prickles.

Using information:
The plant as a whole has narcotic, anodyne and antispasmodic properties. Leaves are used as a local application for rheumatic swellings of the joints, lumbago, sciatica, neuralgia, painful tumours and glandular inflammations, such as mumps; used externally for earache and smoked to relieve spasmodic asthma. Seeds are used externally for piles. Seeds, leaves and roots are used in insanity, fever with catarrh, diarrhoea, skin diseases and cerebral complications. The Marma use to insert thumb in to the fruit and keep for a time to treat finger felon. The seeds are used for asthma and to made men mad in Khagrachari of Chittagong Hill Tracts (Yusuf et al. 2009).

Alcoholic extract of the leaf possesses good antibacterial and antifungal activities (Anwar et al., 2007 & Begum et al., 2007). EtOH(50%) extract of the plant is anthelmintic, anticancer, and also of fruits, spasmogenic and Blood pressure depressant; aquous extract strong nematicidal (Asolkar et al.,1992).


Chemical constituents:
Principal constituents of the plant are a large number of tropane alkaloids including hyoscyamine, hyoscine, littorine, acetoxytropine, valtropine, fastusine, fastusinine, a number of withanolides and various tigloyl esters of tropine and pseudotropine. Fruit pericarp contains β-sitosterol, triterpene, daturanolone and daturadiol.

Seeds contain, daturanolone and fastusic acid in addition to the tropane alkaloids. Calystegines, the nortropane alkaloids with glycosidase inhibitory activity, have also been found in various Datura species (Ghani, 2003). Root contains 3α, 6β-Ditigloyloxytropane, 3α, 6β-ditigloyloxytropan-7β-ol, tigloidine, apohyoscine, hyoscine, 3α-tigloyloxytropane, norhyoscine, meteloidine, hyoscyamine, cuscohygrine and tropine (Rastogi & Mehrotra, 1993).

All over Bangladesh in road sides and other fallow lands.